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Meet Our Team of Preclinical Researchers

Meet Our Team of Preclinical Researchers

With more than 100 years combined experience, Preclinical Translational Services is led by some of the nation’s top preclinical researchers and specialists.

Vince Mendenhall, DVM, PhD

Vince-Mendenhall-ProfileAn internationally renowned experimental surgeon, Vince Mendenhall is known for his innovative surgical techniques, rigorous protocols and deep expertise in medical device development. Mendenhall offers over 40 years of orthopaedic surgical expertise in nearly every animal model available.

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Jay R. Kaplan, PhD

  • Director, Wake Forest Primate Center
  • Section Head, Pathology—Comparative Medicine
  • Professor of Pathology – Comparative Medicine
  • Research interests include cardiovascular behavioral medicine, neurobiology, women’s health, primate biology and behavior, evolutionary psychology, nutrition and behavior, Darwinian medicine, primate genetics

Janice D. Wagner, DVM, PhD, Diplomate ACLAM

  • Professor Emeritus of Pathology
  • Research interests in obesity, diabetes, cardiovascular disease, nutrition and women’s health research
  • Experience with protocol development for numerous preclinical drug assessments in primate models

Mark Cline, DVM, PhD, DACVP

  • Professor of Pathology – Comparative Medicine
  • Expertise and interest in diabetes, drugs/therapeutic agents and pharmaceuticals, infectious diseases
  • Research focusing on the effect of hormonal therapies (hormone replacement after menopause, oral contraceptives, and others) on breast and uterine cancer risk. Recent exciting results indicate that dietary soy supplementation may decrease estrogen-induced cell proliferation and cancer risk in the breast and uterus

Thomas C. Register, Ph.D.

  • Professor of Pathology – Comparative Medicine
  • Clinical Chemistry and Endocrinology Core Laboratory Director
  • Nonhuman primate biomarker development and application

Thomas B. Clarkson, DVM, DACLAM

  • Professor of Pathology – Comparative Medicine
  • One of nation’s foremost investigators in the effects of nutrition on cardiovascular disease
  • Internationally known for use of animal models to better understand human atherosclerosis
  • Research interests include coronary artery atherosclerosis and coronary heart disease in females; new directions in hormone replacement therapy; behavioral and psychosocial influences on chronic diseases; animal models
  • Past chairman of the Council on Arteriosclerosis of the American Heart Association and past president of the American College of Laboratory Animal Medicine

Diann Mendenhall

  • More than 30 years of diverse experience in the GxP medical research profession
  • Seven years of preclinical (GLP) and clinical (GCP) trial support for implantable cardiac devices
  • Four years of experience as a Quality Assurance auditor (GMP) for medical device manufacturing company auditing to FDA regulations and ISO standards
  • Six years of experience in histology field performing SEM (scanning electron microscopy) analysis