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Addiction and Substance Abuse

Addiction and Substance Abuse

The abuse of alcohol and illicit substances has a $375 billion annual price tag in the U.S. as a result of crime, reduced work productivity and health care costs. Moreover, adverse effects of substance abuse go beyond abusers to include their families and friends, as well as innocent victims of abuse-fueled crime and accidents.

Specialists at Preclinical Translational Services have decades of experience using self-administration and dosing paradigms to evaluate the effects of alcohol and illicit substances, as well as therapeutic interventions on behavior and health. Although the team has used a variety of model platforms, particular expertise can be offered in the application of nonhuman primates to problems of substance abuse.

We can:

  • Assess the physiology of nonhuman primate subjects during testing
  • Assess conditioned and unconditioned behaviors during testing
  • Assess the abuse liability of drugs
  • Evaluate pharmaceutical interventions for efficacy as well as potential side effects
  • Design studies to test the effect of therapeutic interventions on non-CNS outcomes, especially changes in metabolism and cardiovascular function

Each year, millions of people suffer from substance abuse disorders, and countless more are affected by someone else’s problem. The scientists and researchers of Preclinical Translational Services have decades of experience examining the effects of alcohol and drugs.

We can:

  • Assess physiology of nonhuman primate subjects during testing
  • Assess conditioned and unconditioned behaviors during testing

Contact us for more information.