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Preclinical Models for Ophthalmology

Preclinical Models for Ophthalmology

The preclinical scientists and surgeons at Wake Forest have broad experience in ocular diseases and procedures, and are experts in corneal and retina-related issues. We have access to standard and advanced technologies for ophthalmological studies such as vertometers, slit lamps, tonometers and optical coherence tomography as well as tools catered to preclinical study management like our electroretinogram; which is specially designed for large and small animals.

Our preclinical services are unique because we can perform your studies on a broad range of preclinical models for ophthalmology such as rabbits and nonhuman primates, providing insight that typical mice and rat studies cannot often achieve. We have the resources to test the efficacy of most ophthalmological devices or procedures, and the experience to provide a timely and discerning perspective on your study outcomes.

Additionally, we have direct clinical connectivity to the ophthalmological experts at Wake Forest Baptist Medical Center’s Department of Ophthalmology. The Department of Ophthalmology employs leading physicians in eye care; about 90% are listed in the Best Doctors in America directory. The department is one of the fastest growing eye centers in the United States and provides over 120,000 patients with high-quality patient care and leading-edge eye treatments and therapies.

Selected Preclinical Models for Ophthalmology

  • Partial penetrating keratoprosthesis
  • Corneal prosthesis/transplant
  • Descemet’s Stripping automated endothelial keratoplasty
  • Continuous infusion to the cornea via catheterization of a transplanted parotid duct
  • Continuous telemetric measurement or intraocular pressure
  • Vitreal implants
  • Sub-retinal implants